Incidence of Βeta-Thalassemia Minor among Healthy Blood Donors
نویسندگان
چکیده
Background: Disorders with a markedly slowed rate of globin chain synthesis are referred to as thalassemia. Hemoglobinopathy is word used describe diseases that cause structurally aberrant hemoglobin. Iron deficiency seen in beta-thalassemia minor, which may change the typically increased HbA2 levels. According World Health Organization (WHO) statistics, 7% global population carries hemoglobin problem. Thalassemia most prevalent hemoglobinopathies, significant genetic issues Pakistan. The prevalence -thalassemia Pakistan around 5%, whereas S or E between 0.5% and 1%. purpose study was determine how common beta thalassemia minor among blood donors. Methods: A total 500 individuals were recruited this cross-sectional who for electro-phoresis September 2015 March 2016 subject investigation. thorough clinical history taken, including information on patient's age, sex, cast, family history, transfusions, physical findings such splenomegaly. Hb Electrophoresis tests performed all samples. Results: Out patients, male 83.1% (n=79) while female 16.9% (n=16). Among individuals, 18.3% (n=94) found positive cases electrophoresis technique remaining 406 patients observed negative. All categorised four (04) different groups based age; highest number 18-30 years age group 69 followed by 31-40 (n=19), 41-50 (n=5.3), 51-60 (n=01). 94 (18.3%) had abnormal minor. Of them, 79 (84.4%) men 16 (17.2%) women. Conclusion: Many continue struggle problems. Preventive interventions, pre-marriage carrier status identification screening required lower incidence major forcing couples abort their pregnancies. Keywords: Hemoglobin Disorders, Thalassemia, β-Thalassemia, Healthy Blood Donors,
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ژورنال
عنوان ژورنال: Pakistan Journal of Medical and Health Sciences
سال: 2023
ISSN: ['1996-7195']
DOI: https://doi.org/10.53350/pjmhs2023171746